Gallbladder cancer is a rare but aggressive cancer that develops in the gallbladder, a small organ located beneath the liver that stores bile.
Early-stage gallbladder cancer often has no clear symptoms. As it progresses, symptoms may include persistent abdominal pain (especially upper right side), jaundice (yellowing of skin and eyes), nausea and vomiting, unexplained weight loss, loss of appetite, and abdominal swelling.
Risk factors include long-standing gallstones, chronic gallbladder inflammation, gallbladder polyps, porcelain gallbladder, family history of gallbladder cancer, female gender, and age above 50 years.
Diagnosis may involve ultrasound, CT scan or MRI, PET scan, blood tests (including liver function tests), and biopsy in selected cases. Sometimes gallbladder cancer is incidentally discovered after gallbladder removal surgery for gallstones.
Surgery is the primary and potentially curative treatment if detected early. Advanced cases may require chemotherapy, targeted therapy, or palliative treatment for symptom relief. Treatment depends on the stage of cancer.
Surgical options may include simple cholecystectomy (for very early-stage disease), extended cholecystectomy (removal of gallbladder along with part of the liver and nearby lymph nodes), and radical surgery in advanced cases. The surgical approach depends on tumor stage and spread.
Gallbladder cancer can be cured if diagnosed at an early stage and completely removed surgically. Advanced-stage cancer is more challenging to treat but can be managed.
Most patients recover within 3–6 weeks, depending on the extent of surgery and overall health.
Yes, gallbladder cancer tends to spread early to the liver, lymph nodes, and nearby organs. That's why early detection is critical.
Most people with gallstones do NOT develop cancer. However, long-standing untreated gallstones may increase the risk.
Regular follow-up includes clinical examination, blood tests, imaging (CT/MRI), and monitoring for recurrence.
You should seek specialist consultation if you have persistent right upper abdominal pain, unexplained jaundice, suspicious imaging findings, or gallbladder cancer found incidentally after surgery. Early expert evaluation improves outcomes.